News

On Thursday November 16th, Orphazyme A/S (Orphazyme) initiated its first trading day on Nasdaq Copenhagen, Denmark. The IPO was several time oversubscribed at an initial price of DKK 80 per share raising 80M€. This gives Orphazyme a market capitalisation of DKK 1,594 million after completion of the Offering (excluding a 15% overallotment option).

Orphazyme is a Danish biotech company with a late stage orphan drug pipeline, developing new treatment options for orphan protein misfolding diseases. The Company was founded in 2009 based on early scientific discovery in heat shock proteins (“HSPs”). Since inception, the Company has translated scientific discovery into a late stage clinical development programme. The Company is headquartered in Copenhagen and currently has 30 employees. The Company focuses on severe and mostly fatal diseases with a high unmet need, and with a particularly strong commitment to neuromuscular diseases and a group of severe genetic diseases called lysosomal storage diseases. The Company plans to pursue development of its lead candidate through to registration in the EU and the United States after which launch and commercialization is expected to be undertaken by the Company. The lead candidate arimoclomol is in development as a potential treatment for four orphan diseases; two neuromuscular diseases, sporadic Inclusion Body Myositis (“sIBM”) and Amyotrophic Lateral Sclerosis (“ALS”), and two lysosomal storage diseases, Niemann Pick type C (“NPC”) and Gaucher disease.

Sunstone Capital acted as co-lead investor of Orphazyme series A financing in February 2011 through an investment from its Sunstone Life Science Fund II, and has participated in all subsequent financing rounds. Since the first investment, Sunstone has been represented on the Board by Sten Verland, senior partner, supporting the company in strategic and operational matters since then. Sten Verland will continue on the Board after the IPO. This transaction represents one of the more significant recent European biotechnology IPOs, and is a validation of Sunstone’s investment strategy as well as yet another example of an increasingly active and competitive European biotech industry.

Sunstone Life Science Fund II portfolio company Orpahzyme, publishes an offering circular and the indicative price range in connection with its intended initial public offering (“IPO” or the “Offering”) and subsequent admission to trading and official listing of its shares on Nasdaq Copenhagen.

For a further description of the Offering, please refer to www.orphazyme.com.

Sunstone Life Science Fund III portfolio company  Opsona Therapeutics Ltd (‘Opsona’), the innate immune drug and development company focused on novel therapeutic approaches to treat oncology, autoimmune and other inflammatory diseases, today announced that it has received orphan drug designation (ODD) from United States Food and Drug Administration for myelodysplastic syndromes (MDS).

Sunstone Life Science Fund II portfolio company Orpahzyme, announces its intention to launch an Initial Public Offering (“IPO” or “Offering”) of its shares and to apply for admission to trading and official listing on Nasdaq Copenhagen. The intended IPO is expected to consist of an issue of new shares to raise gross proceeds of approximately DKK 600 million to support the Company’s strategy by primarily funding on-going and planned clinical trials within four orphan diseases. The total offer size will be announced in connection with the publication of a prospectus by the Company.

For full text of the announcement, please refer to www.orphazyme.com

Starting immediately, Arcoma will be selling Arcoma branded systems integrated with Canon image software and detectors throughout Europe, the Middle East and Africa.

Until now, Canon distributors have bought the image software and the detectors directly from Canon Europe, having two points of sourcing for a complete system. This new agreement allows Arcoma to deliver the completely integrated system, ensuring functionality, quality and reducing installation time for its customers. The agreement will increase Arcoma sales by approx. 25 MSEK per year and will strengthen the Arcoma brand in Europe considerably.

“We are proud to be able to sell the complete Arcoma branded systems with the Canon detectors throughout EMEA. The strengthened alliance with Canon allows us to pre-stage systems prior to installation, thus reducing installation time for end-users and ensuring system functionality and quality. This is further an important part of Arcoma’s strategy to strengthen the Arcoma brand and increase its product offering”, says CEO Mikael Högberg.